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. 2008 Aug 13;28(33):8246–8256. doi: 10.1523/JNEUROSCI.1941-08.2008

Figure 6.

Figure 6.

Blocking phosphorylation of p65 at S536 in SCG neurons abolishes neurite growth inhibition induced by TNFα and p65 overexpression. A–C, Total neurite length (A), number of branch points (B), and Sholl profiles (C) of the neurite arbors of P0 SCG neurons transfected 3 h after plating with the YFP plasmid together with either a pcDNA3.1 control plasmid, p65 plasmid, or a S536A-p65 plasmid and cultured for an additional 24 h. D–F, Total neurite length (D), number of branch points (E), and Sholl profiles (F) of the neurite arbors of P0 SCG neurons transfected 3 h after plating with the YFP plasmid and either the pcDNA3.1 control plasmid or S536A p65 plasmid and cultured for an additional 24 h with or without 10 ng/ml TNFα. The combined results of three separate experiments are plotted (means and SEs of the data from >150 neurons for each condition). Statistically significant difference from control-transfected neurons is indicated (**p < 0.001).