Table 1.
Summary of proteins reprogramming methods.
Cell types | Proteins | Vectors | Culture time with proteins | Culture time without proteins | Use of VPA | References |
---|---|---|---|---|---|---|
Mouse embryonic fibroblasts (MEF) | Oct4, Sox2, Klf4, (c-Myc) | 11R | Overnight (12 hours) | 36 hours | Y | [20] |
Human newborn fibroblasts (HNF) | Oct4, Sox2, Klf4, c-Myc | 9R | 16 hours | 6 days | N | [21] |
Human foreskin fibroblast (HFF) | Oct4, Sox2, Klf4, c-Myc, (Nanog) | TAT | 2 hours | 48 hours | Y | [26] |