Table 2. Genotype counts, associations, and odds ratios in participants with high myopia and control participants.
| Single nucleotide polymorphisms | Genotype | High myopia |
Control 1 |
Control 2 |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | n | Nominal p value* | Adjusted p value† | Adjusted OR (95% CI) | n | Nominal p value* | Adjusted P value† | Adjusted OR (95% CI) | ||
|
rs2071754 (C/T) |
CC |
326 |
90 |
0.61 |
0.26 |
1.12 (0.92-1.38) |
232 |
0.485 |
0.497 |
1.04 (0.93-1.17) |
| CT |
632 |
156 |
466 |
|||||||
| TT |
344 |
87 |
225 |
|||||||
|
rs644242 (C/A) |
CC |
1052 |
258 |
0.12 |
0.026 |
0.69 (0.49-0.96) |
710 |
0.0153 |
0.0152 |
0.79 (0.66-0.96) |
| CA |
237 |
68 |
195 |
|||||||
| AA |
14 |
7 |
18 |
|||||||
|
rs3026354 (A/G) |
AA |
544 |
142 |
0.33 |
0.78 |
1.03 (0.83-1.29) |
376 |
0.611 |
0.638 |
0.97 (0.86-1.10) |
| AG |
590 |
155 |
421 |
|||||||
| GG | 171 | 34 | 126 | |||||||
* Differences in the observed genotypic distribution were examined by a chi-square test for trend. † Age and sex adjustment were performed based on a logistic regression model. CI: Confidence interval, OR: Odds ratio.