. 2011 Jul 20;4:47–63. doi: 10.2147/PGPM.S20317

Table 2.

Association between SNPs in ERCC1 and clinical outcome

Cancer	rs	SNPs	Alternate names	Reference	n	Outcome^a
NSCLC	rs11615	Asn118 Asn	C118T; 354 T > C; 19007 T > C; 3525 C > T	Zhou et al⁶³	128	0
				Gandara et al (2005)^b	526	0
				Suk et al⁵⁹	214	0 (toxicity)
				De Las Penas et al⁷¹,^b	135	0
				Tibaldi et al⁶¹	65	0
				Takenaka et al⁷³	122	0
				Vinolas et al⁶²,^b	94	0
				Park et al⁶⁴	178	(1); 1 for stage III
				Ryu et al⁶⁵	109	1
				Isla et al⁶⁸	62	1
				Su et al⁶⁶	230	1
				Kalikaki et al⁵⁷	119	1
				Okuda et al³⁸	90	1
				Yin et al⁶⁷	257	1
				Li et al⁷⁰,^b	115	2
				Zhou et al⁶⁹,^b	130	2
	rs3212986	C8092A	14443 C > A	Zhou et al⁶³	128	1
				Suk et al⁵⁹	214	1 (toxicity)
				Park et al⁶⁴	178	0
				Okuda et al³⁸	90	1
				Takenaka et al⁷³	122	1
				Kalikaki et al⁵⁷	119	2
				Li et al⁷⁰,^b	115	2
HNSCC	rs3212986	C8092A	14443 C > A	Quintela-Fandino et al⁷⁴	103	−1
	rs735482	Lys259Thr	1264 A > C	Grau et al⁷⁵,^b	47	0
	rs735482	Lys259Thr	1264 A > C	Carles et al⁷⁶	108	1 (but only 4% of carrier)

Notes:

Outcome for variable allele, 0 = non significant, (1) = trend to worse, 1 = worse, (2) = trend to better, 2 = better;

prospective study.

Abbreviations: HNSCC, head and neck squamous cell carcinoma; NSCLC, non-small cell lung cancers; rs, reference SNP; SNPs, single nucleotide polymorphisms.