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Multiple linear regression models for estimation of methadone dose based on weight and ABCB1 and OPRM1 genetic variability
| Model variables | Model adjusted R2 | P value |
|---|---|---|
| Weight | 0.054 | 0.013 |
| Weight, ABCB1 haplotype in OPRM1 118A1A subjects | 0.478 | 0.022 |
| ABCB1 haplotype in OPRM1 118A1A subjects | 0.482 | 0.007 |
| Weight, OPRM1 118A > G genotype in ABCB1 AGCGC/AGTTT subjects | 0.201 | 0.082 |
| OPRM1 118A > G genotype in ABCB1 AGCGC/AGTTT subjects | 0.229 | 0.03 |
