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Vasodilator response of isolated and pressurized porcine retinal arterioles to bradykinin. Concentration-dependent vasodilation to bradykinin was significantly reduced in a similar manner following all three time periods of diabetes mellitus: (A) 2 weeks (control = 15 pigs; diabetes = 17 pigs), (B) 6 weeks (control = 4 pigs; diabetes = 5 pigs), and (C) 12 weeks (control = 4 pigs; diabetes = 9 pigs). *P < 0.05 versus control.
