Figure 3. Effect of NPB112 on levels of blood glucose (A), body weight (B), insulin (C) and glucagon (D) in DIO mice before and every week after injection of vehicle of NPB112 for 6 weeks and 4 weeks of recovery period (n = 24 per group).

Values are expressed as mean SEM (A and D) *, p<0.001 and **, P<0.05 compared to control mice with vehicle. (B and C) *, p<0.01 and **, P<0.05 compared to control mice with vehicle.