Skip to main content
. 2012 Dec 3;7(12):e50954. doi: 10.1371/journal.pone.0050954

Table 1. Pharmacokinetic parameters of NPB112 after single intravenous or intraperitoneal administration of 5 mg/kg NPB112 to Sprague-Dawley rats.

Intravenous administration(n = 5) Intraperitoneal administration(n = 5)
Tmax (h) NA 24.0±0.0
Cmax (ug/ml) NA 28.4±3.5
AUClast (ug•h/ml) 3354.2±802.9 2766.1±593.5
Clearance (l/h/kg) 0.001±0.0004 NA
T1/2 (h) 49.8±28.2 86.8±52.8
F (%) NA 103.3±45.5

NA: not applicable.