Table 1. Clinical and biochemical characteristics of patients with T2DM treated with standardized IT compared with individuals under oral anti-diabetic therapy (OT).
Characteristics | Baseline N = 8 (oral medication, OT) (mean ± SEM) | Baseline N = 10 (standardized IT) (mean ± SEM) | Day 10 N = 10 (standardized IT) (mean ± SEM) | Follow up N = 7 (standardized IT) (mean ± SEM) |
Age (years) | 53±2 | 58±3 | – | – |
Sex (f/m) | 4/4 | 4/6 | – | – |
Diabetes duration (years) | 3±1 | 9±2‡ | – | – |
HbA1c (%) | 9.8±0.7 | 11.1±0.4 | n. a. | 8.3±0.4† |
BMI (kg/m2) | 30±1.7 | 30±1.7 | 30±1.7 | 30±2.3 |
BP syst./diast. (mmHg) | 137±9/77±3 | 134±4/75±4 | 122±2/71±5 | 138±3/81±4 |
Plasma glucose (mg/dl) | 182±14 | 231±19 | 150±8* | 146±25 |
Cholesterol (mg/dl) | 217±22 | 195±9 | 154±8* | 163±15† |
LDL cholesterol (mg/dl) | 135±19 | 117±10 | n. a. | 88±13 |
Triglycerides (mg/dl) | 225±64 | 192±30 | 166±16 | 147±41 |
HDL- cholesterol (mg/dl) | 50±5 | 40±3 | n. a. | 45±4 |
Albumin (g/l) | 43±1.6 | 44±1.0 | n. a. | 44±0.7 |
Creatinine (mg/dl) | 0.84±0.03 | 0.94±0.11 | n. a. | 0.89±0.11 |
Albumin-Crea-Quot (mg/dl) | 14±2.4 | 31±10.4 | n. a. | 19±7.3 |
Pro BNP (pg/ml) | 38±9 | 124±66 | n. a. | 81±42 |
Insulin dose (IU/day) | n. a. | 0±0 | 39±7* | 49±10† |
Values are mean ± SEM.
n. a., not assessed.
p<0.05 baseline IT vs. 10th day of IT,
p<0.05 baseline IT vs. follow up IT,
p<0.05 baseline oral medication vs. baseline standardized IT.