Table 3.
Results of multiple logistic regression of lung cancer risk on sex, age at randomization, family history of lung cancer, cotinine, total NNALa, PheTb, and years of cigarette smoking
| VARIABLES | 95% Confidence Limits | P | ||
|---|---|---|---|---|
| ORc | Lower | Upper | ||
| Sex (men vs. women) | 1.38 | 0.68 | 2.79 | 0.3701 |
| Age at randomization | 1.10 | 1.02 | 1.18 | 0.0187 |
| Family history of lung cancer | 2.57 | 0.87 | 7.60 | 0.0891 |
| Cotinined | 0.85 | 0.59 | 1.23 | 0.3947 |
| Total NNALa,d | 1.57 | 1.08 | 2.28 | 0.0182 |
| PheTb,d | 1.23 | 0.88 | 1.72 | 0.2274 |
| Years of cigarette smokinge | 1.54 | 0.86 | 2.75 | 0.1454 |
NNAL = 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol; total includes its glucuronides.
PheT = r-1,t-2,3,c-4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene
OR = odds ratio
Represents OR associated with a unit standard deviation increase
Represents OR associated with a 10-year increase in smoking duration