Table 1.
Demographic and clinical characteristics of the incident cardiomyopathy study population (N =3,035) according to HAART initiation by end of follow-up, PACTG 219/219C, 1993–2007.
| Characteristic | Total N (%) | Initiated HAART N (%) | Never initiated HAART N (%) | P-value |
|---|---|---|---|---|
| 3035 (100) | 2515 (83) | 520 (17) | ||
| Age (years) | 0.02 | |||
| ≤ 1 | 338 (11) | 281 (11) | 57 (11) | |
| 2–5 | 997 (33) | 796 (32) | 201 (38) | |
| 6–10 | 1086 (36) | 916 (36) | 170 (33) | |
| >10 | 614 (20) | 522 (21) | 92 (18) | |
| Birth cohort | <0.001 | |||
| 1975–1989 | 992 (33) | 766 (30) | 226 (43) | |
| 1990–1995 | 1475 (48) | 1207 (48) | 268 (52) | |
| 1996–2005 | 568 (19) | 542 (22) | 26 (5) | |
| Sex | 0.23 | |||
| Male | 1485 (49) | 1243 (49) | 242 (47) | |
| Female | 1550 (51) | 1272 (51) | 278 (53) | |
| Race/Ethnicity | <0.001 | |||
| White/Other | 470 (16) | 377 (15) | 93 (18) | |
| Black | 1770 (58) | 1509 (60) | 261 (50) | |
| Hispanic | 795 (26) | 629 (25) | 166 (32) | |
| Maternal ARV use during pregnancy | 0.02 | |||
| Yes | 310 (10) | 271 (11) | 39 (8) | |
| No | 2457 (81) | 2014 (80) | 443 (85) | |
| Missing | 268 (9) | 230 (9) | 38 (7) | |
| Birth Weight | 0.83 | |||
| < 2500 grams | 746 (25) | 615 (25) | 131 (25) | |
| ≥ 2500 grams | 2167 (71) | 1794 (71) | 373 (72) | |
| Missing | 122 (4) | 106 (4) | 16 (3) | |
| CDC clinical category | 0.68 | |||
| Not C | 2237 (74) | 1850 (74) | 387 (74) | |
| C | 798 (26) | 665 (26) | 133 (26) | |
| Nadir CD4% | 0.24 | |||
| < 15 | 809 (27) | 657 (26) | 152 (29) | |
| 15–24 | 878 (29) | 740 (30) | 138 (26) | |
| ≥ 25 | 1188 (39) | 987 (39) | 201 (39) | |
| Missing | 160 (5) | 131 (5) | 29 (6) | |
| Peak Viral load (copies/ml) | 0.02 | |||
| < 10,000 | 720 (24) | 643 (26) | 77 (15) | |
| 10,000–99,999 | 464 (15) | 397 (16) | 67 (13) | |
| ≥ 100,000 | 611 (20) | 556 (22) | 55 (10) | |
| Missing | 1240 (41) | 919 (36) | 321 (62) |