Table 3.
Correlation analyses of stress measures, frequency of current cannabis use and severity of symptoms with Area Under the Curve (AUC) of cortisol secretion during the day and the AUC with respect to increase (AUCi) of the cortisol awakening response in first-episode psychosis patients and healthy controls
Patients |
Controls |
|||
---|---|---|---|---|
AUC cortisol During day |
AUCi cortisol Awakening |
AUC cortisol During day |
AUCi cortisol Awakening |
|
Number of stressful life events |
r=−0.36 | r=0.15 | r=0.42 | r=0.14 |
p=0.014 | p=0.3 | p=0.013 | p=0.4 | |
Perceived stress scale |
r=−0.25 | r=0.18 | r=0.11 | r=−0.12 |
p=0.1 | p=0.2 | p=0.5 | p=0.5 | |
Childhood trauma |
r=−0.23 | r=0.28 | r=0.12 | r=−0.26 |
p=0.2 | p=0.077 | p=0.5 | p=0.2 | |
Tobacco smoking |
r=0.012 | r=−0.022 | r=−0.111 | r=0.206 |
p=0.9 | p=0.9 | p=0.5 | p=0.2 | |
Frequency of current cannabis use |
r=−0.27 | r=0.32 | r=−0.06 | r=0.02 |
p=0.074 | p=0.029 | p=0.7 | p=0.9 | |
Severity of symptoms |
r=−0.04 | r=0.01 | - | - |
p=0.8 | p=1.0 | - | - |