Skip to main content
. 2012 Aug 21;13(4):1103–1109. doi: 10.1208/s12249-012-9830-3

Table IV.

Solubility of Drugs in Pure Lipid Components at 40°C

Lipid or cosolvent Genistein (mg/g) Probucol (mg/g) Nifedipine (mg/g) Indomethacin (mg/g)
Soybean oil 0.059 86.33 1.56 2.38
Castor oil 3.02 67.92 7.19 22.41
Miglyol 812 0.34 161.79 4.78 6.04
Capmul MCM 4.12 75.48 14.86 31.68
Maisine 35-1 0.51 74.38 5.17 13.48
Glyceryl monooleate (GMO) 0.65 39.18 6.04 15.42
Capmul PG-8 7.14 183.31 26.61 44.77
Lauroglycol 3.27 157.84 12.81 26.82
Labrasol 51.17 105.88 69.04 108.06
Labrafil M 1944 CS 1.61 118.82 8.75 18.21
Plurol oleique CC497 1.31 57.78 4.83 17.14
Caprol MPGO 3.89 61.25 5.56 47.27
PEG400 101.12 29.40 94.41 134.15
Propylene glycol 12.29 2.10 10.72 21.66
Ethanol 16.49 224.74 46.53 65.04
Polysorbate 80 66.08 87.83 69.76 119.42
Cremophor RH40 53.74 61.86 85.75 118.77
Vitamin E TPGS 33.85 88.41 65.05 86.49