Table III.

Ex vivo Drug Release and Skin Deposition Profile of Lopinavir from Various Formulations

S. No.	Parameters	Plain gel	Niosomal dispersion	Niosomal gel	Ethosomal gel
1	% drug releasea	6.43 ± 0.21	18.32 ± 0.18	21.24 ± 0.23	11.15 ± 0.15
2	% skin depositiona	10.21 ± 0.22	22.65 ± 0.35	24.45 ± 0.64	54.63 ± 0.29
3	% drug retained on the surfacea	83.42 ± 0.77	58.35 ± 1.23	53.82 ± 0.79	33.42 ± 0.45

^aValues represented as mean ± SD (n = 3)