Table V.

In vivo Pharmacokinetic Parameters of Lopinavir-Loaded Niosomal (F3c) Gel Compared with Its Oral Suspension (OS)

Formulations	Pharmacokinetic parameters
	C max a (μg/ml)	T max (h)	AUC0→12 (h × μg/ml)	AUC0→∞ (h × μg/ml)
OS	5.8 ± 0.2	4	16.19	52.94
F3c gel	7.9 ± 0.2	4	24.34	72.87

C _max peak plasma concentration, T _max peak time, AUC _0→∞ complete area under the PDC versus time curve

^aValues represented as mean ± SD (n = 6)