Figure 3.
Pathways for synthesis of phospholipids in E. coli. The following enzymes with their respective genes named carry out: 1. CDP-diacylglycerol synthase (CdsA); 2. phosphatidylserine synthase (PssA); 3. phosphatidylserine decarboxylase (Psd); 4. phosphatidylglycerophosphate synthase (PgsA); 5. phosphatidylglycerophosphate phosphatase (Pgp) encoded by three genes; 6. cardiolipin synthase (Cls) encoded by three genes with one substrate being PG in all three cases and the second substrate for {ClsA} and [ClsC] indicated by the brackets. Definitive identification of the second substrate for ClsB has not been established; 7. Phosphatidylglycerol:pre-membrane derived oligosaccharide (MDO) sn-glycerol-1-P transferase (MDO synthase); 8. diacylglycerol kinase (DgkA).