Table 4.
Odds ratios for race/ethnicity, time to diagnosis and risk of advanced Stage breast cancer, 2000–2007
| Stage II vs. Stage I N=8,546 |
Stage III/IV vs. Stage I N=3,514 |
|||||
|---|---|---|---|---|---|---|
| Characteristic | Model 1: Age and center OR (95% CI) |
Model 2: Race and time to Diagnosis OR (95% CI) |
Model 3: Multivariable OR (95% CI) |
Model 1: Age and Center OR (95% CI) |
Model 2: Race and time to diagnosis OR (95% CI) |
Model 3: Multivariable OR (95% CI) |
| Race/ethnicity | ||||||
| White | 1.00 (REF)* | 1.00 (REF)* | 1.00 (REF)@ | 1.00 (REF)* | 1.00 (REF)* | 1.00 (REF)@ |
| Hispanic | 1.31 (1.14, 1.48) | 1.27 (1.12, 1.45) | 1.10 (0.96, 1.28) | 1.40 (1.18, 1.64) | 1.28 (1.09, 1.51) | 0.97 (0.82, 1.16) |
| Black | 1.40 (1.25, 1.57) | 1.37 (1.22, 1.54) | 1.17 (1.03, 1.32) | 2.13 (1.86, 2.44) | 2.00 (1.75, 2.30) | 1.50 (1.29, 1.74) |
| Asian | 1.15 (0.96, 1.37) | 1.14 (0.95, 1.36) | 1.12 (0.93, 1.35) | 0.92 (0.73, 1.17) | 0.89 (0.70, 1.14) | 0.90 (0.70, 1.16) |
| Time to diagnosis | Symptomatic women N=5,840 | Symptomatic women N=2,872 | ||||
| 0–30 (days) | 1.00 (REF)* | 1.00 (REF)* | 1.00 (REF)* | 1.00 (REF)* | 1.00 (REF)* | 1.00 (REF)* |
| 30–59 | 0.97 (0.87, 1.08) | 0.96 (0.86, 1.07) | 0.95 (0.85, 1.06) | 1.05 (0.91, 1.20) | 1.03 (0.90, 1.18) | 1.02 (0.89, 1.17) |
| 60–89 | 0.92 (0.79, 1.06) | 0.91 (0.78, 1.05) | 0.90 (0.77, 1.04) | 1.27 (1.07,1.51) | 1.25 (1.05, 1.49) | 1.22 (1.03, 1.46) |
| 90–179 | 1.09 (0.94, 1.25) | 1.08 (0.93, 1.24) | 1.06 (0.92, 1.22) | 1.71 (1.46, 2.01) | 1.68 (1.43, 1.98) | 1.62 (1.37, 1.91) |
| ≥ 180 | 1.02 (0.89, 1.18) | 1.01 (0.87, 1.16) | 1.01 (0.88, 1.17) | 1.96 (1.67, 2.30) | 1.93 (1.64, 2.26) | 1.92 (1.63, 2.26) |
| Time to diagnosis | Women with abnormal mammograms N=2,706 | Women with abnormal mammograms N=642 | ||||
| 0–30 (days) | 1.00 (REF)* | 1.00 (REF)* | 1.00 (REF)* | 1.00 (REF)* | 1.00 (REF)* | 1.00 (REF)* |
| 30–59 | 0.83 (0.75, 0.93) | 0.83 (0.74, 0.93) | 0.82 (0.74, 0.92) | 0.66 (0.53, 0.82) | 0.64 (0.52, 0.80) | 0.63 (0.50, 0.78) |
| 60–89 | 0.83 (0.69, 1.01) | 0.82 (0.67, 0.99) | 0.81 (0.66, 0.98) | 0.79 (0.55, 1.14) | 0.73 (0.51, 1.06) | 0.73 (0.51, 1.05) |
| 90–179 | 0.65 (0.51, 0.84) | 0.64 (0.50, 0.82) | 0.63 (0.49, 0.81) | 1.09 (0.75, 1.59) | 1.01 (0.69, 1.48) | 1.00 (0.68, 1.46) |
| ≥ 180 | 0.90 (0.70, 1.17) | 0.89 (0.69, 1.15) | 0.89, (0.69, 1.15) | 1.62 (1.13, 2.32) | 1.53 (1.07, 2.20) | 1.53 (1.07, 2.20) |
Model 1. Estimates come from two models: 1) included race/ethnicity, age at diagnosis and NCCN center; 2) included time to diagnosis, age at diagnosis and NCCN center.; Model 2. Includes age at diagnosis, NCCN center with mutual adjustment for race/ethnicity and time to diagnosis; Model 3: Includes 2 plus employment status, educational status, body mass index at presentation, insurance status, and menopausal status at diagnosis.
*
Type 3 p-value <0.0001;
@
Type 3 p-value=0.0001