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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Toxicol In Vitro. 2012 Aug 16;27(1):367–377. doi: 10.1016/j.tiv.2012.08.012

Figure 3. HEDS decreases levels of protein thiols (PSH) in glucose-deprived human colon cancer cells independent of p53 status.

Figure 3

The effect of glucose deprivation on intracellular protein thiol levels was determined in the absence or presence of HEDS at the indicated concentration in cells that are radiation-sensitive and p53 wild-type HCT116 (A) or radiation-resistant and p53 mutant HT29 (B). Mean for three to five independent experiments are shown with SD. A statistically significant reduction in PSH levels in cells cultured in glucose-deprived media occurred after HEDS treatment (0.7 mM, *P<0.01; 3.3 mM, **P<0.001).