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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Toxicol In Vitro. 2012 Aug 16;27(1):367–377. doi: 10.1016/j.tiv.2012.08.012

Figure 7. Glucose deprivation limits the NADPH recycling.

Figure 7

Glucose-dependent regulation of NADPH in p53 wild type HCT116 (A) and HT29 (B) human colon cancer cells treated with HEDS. Mean levels quantified by HPLC/Fluorescence are presented with standard deviation in the data. A statistically significant decrease in cells with normal glucose at 3.3 mM HEDS (**P<0.001) and a higher decrease in NADPH occurred in glucose-deprived cells as compared to normal glucose independent of p53 status in the presence of 0.7 mM (*P<0.01) or 3.3 mM (**P<0.001) HEDS. A st