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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Bone. 2012 Sep 17;52(1):93–101. doi: 10.1016/j.bone.2012.09.011

Figure 4. Adherent LPS inhibits bone-to-implant contact through TLR4.

Figure 4

The percentage of bone-to-implant contact (A) and the percentage of peri-implant bone (B) in wild-type C57BL/6J mice, TLR4−/− mice, TLR2−/− mice and TLR4−/−;TLR2−/− mice one week after implantation with rigorously cleaned implants or implants with 1 × 104 EU/m2 of adherent LPS. Representative histological cross-sections, which are closest to the mean in A, at one week after implantation in mice with implants with 1 × 104 EU/m2 of adherent LPS (C). Arrows denote bone-to-implant contact. Statistical analysis was by Two-Way ANOVA. n=8–10.