Table 3.
βAR Receptor Polymorphism | Discovery cohort 2001-2006 | Validation cohort 2007-2008 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Overall | Caucasian | Hispanic | African-American | Asian | Overall | Caucasian | Hispanic | African-American | Asian | |
B1AR 1165 (Arg389Gly) | ||||||||||
CC | 59% | 56% | 70% | 44% | 61% | 63% | 63% | 73% | 39% | 61% |
CG | 34% | 37% | 25% | 42% | 32% | 32% | 33% | 24% | 41% | 36% |
GG | 7% | 7% | 5% | 14% | 7% | 6% | 5% | 3% | 20% | 3% |
B1AR 145 (Ser49Gly) | ||||||||||
AA | 71% | 78% | 56% | 63% | 74% | 67% | 77% | 46% | 64% | 71% |
AG | 25% | 20% | 35% | 29% | 21% | 28% | 22% | 45% | 26% | 21% |
GG | 4% | 1% | 9% | 8% | 5% | 5% | 1% | 10% | 10% | 9% |
B2AR 46 (Gly16Arg) | ||||||||||
GG | 36% | 39% | 36% | 25% | 27% | 40% | 40% | 37% | 43% | 27% |
AG | 46% | 45% | 47% | 54% | 45% | 38% | 39% | 40% | 36% | 39% |
AA | 18% | 15% | 18% | 21% | 28% | 22% | 21% | 24% | 21% | 33% |
B2AR 79 (Gln27Glu) | ||||||||||
CC | 50% | 37% | 63% | 66% | 69% | 50% | 35% | 65% | 64% | 73% |
CG | 38% | 43% | 32% | 29% | 29% | 37% | 48% | 27% | 18% | 20% |
GG | 13% | 20% | 5% | 5% | 2% | 14% | 17% | 8% | 18% | 7% |