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. Author manuscript; available in PMC: 2013 Oct 22.

Published in final edited form as: Matrix Biol. 2012 Oct 22;31(7-8):380–388. doi: 10.1016/j.matbio.2012.10.001

Table 1.

Gelatin binding of wild-type MMP-2 and variants.

MMP-2 variant	K_d
MMP-2 variant	Apparent (M × 10⁻⁹)	Relative (versus wild-type)
Wild-type	1.03 ± 0.07	1.0
R252A	2.58 ± 0.99	2.5
F297A	2.80 ± 0.95	2.7
R368A	3.56 ± 1.35	3.5
R252A/F297A	5.84 ± 2.77	5.7
R252A/R368A	7.49 ± 1.76	7.3
F297A/R368A	37.6 ± 2.0	36.5
R252A/F297A/R368A	ND	ND

ND, not determined