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. Author manuscript; available in PMC: 2012 Dec 4.
Published in final edited form as: Cell Rep. 2012 Nov 21;2(5):1151–1158. doi: 10.1016/j.celrep.2012.10.013

Figure 3. Induction of IL-17RC by IL-17A and IL-17F in monocytes and characteristics of IL-17RC+ monocytes. (Data are expressed as the means ± S.E.).

Figure 3

(A) FACS staining of IL-17RC induced by IL-17A and IL-17F in THP1 cells.

(B) FACS staining of IL-17RC induced by IL-17A and IL-17F in primary CD14+ monocytes. See also Figure S3.

(C) Relative activity of NF-κB measured by TransAM NF-κB p65 Transcription Factor ELISA Kit.

(D) Scatter plot showing the genome-wide expression difference between sorted IL-17RC+ and IL-17RC− THP1 cells.

(E) Relative expression of CXCR1, CXCR2, CXCR4, and CXCR7 mRNA in sorted IL17RC+ and IL17RC− THP1 cells.

(F) Relative expression of CXCR1, CXCR2, CXCR4, and CXCR7 mRNA in sorted IL17RC+CD14+ and IL17RC−CD14+ monocytes from two AMD patients. Undet, undetectable.

(G) Relative expression of CXCR1, CXCR2, CXCR4, and CXCR7 mRNA in primary CD14+ monocytes stimulated by IL-17A or IL-17F overnight. Undet, undetectable.