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Effect of LKE on the expression of CRMP2, PARP-1 and SIRT-1. (A, B and C) No differences were observed between sham and LKE pre-treated sham. LKE pre-treatment significantly upregulated the expression of total CRMP2 and SIRT-1 and decreased the expression of the caspase cleaved fragment of PARP-1. Corresponding graphs show the densitometric analysis normalized to actin and histone proteins, respectively.
