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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Neurochem Int. 2012 Oct 2;61(8):1357–1363. doi: 10.1016/j.neuint.2012.09.013

Figure 4.

Figure 4

LKE elicits neuritogenesis in mice cortical neurons. Top panel: control neurons without any treatment. The nucleus is stained with DAPI (blue stain), F-actin (phalloidin green stain), and CRMP2 (red stain). The far right image shows the merged overlay of all the pictures. t-BuOOH treatment induced CRMP2 localization into the nucleus and collapse of F-actin filaments. Pre-treatment with LKE (200 μmol/L) induced the expression of CRMP2 and F-actin in axons and dendrites. Each experiment was conducted in triplicate and repeated three times with different primary culture batches.