Table 1.

The spectrum of BRCA2 and RAD52 across various species.

		Biochemical activity
Species		Mediator	Annealer	HR Phenotype
S. cerevisiae	No BRCA2
	Rad52	Yes	Yes	++
U. maydis	Brh2	Yes	Yes	++
	Rad52	Low	Yes	−
A. thaliana	BRCA2	?	?	+
	Rad52	?	?	+
D. melanogaster	BRCA2	?	?	+
	No Rad52
C. elegans	BRC-2	Yes	Yes	++
	No Rad52
H. sapiens M. musculus	BRCA2	Yes	No	++
	RAD52	No	Yes	(+)

++ = strong phenotype, + = intermediate phenotype, (+) = weak phenotype; ? = unknown/no published reports identified.