. Author manuscript; available in PMC: 2013 Dec 15.

Published in final edited form as: Toxicol Appl Pharmacol. 2012 Sep 10;265(3):308–315. doi: 10.1016/j.taap.2012.08.031

Table 4.

Serum PON1 activity towards chlorpyrifos-oxon and paraoxon respective to PON1 55 and PON1 192 genotype

PON1 genotype	N	CPOase (U/l)		POase (U/l)

		Baseline	Post CPF exposure	Baseline	Post CPF exposure
QQ/LL	11	4196 (2854 – 5982)	4601 (2977 – 7030)	54 (36 – 86)	58 (36 – 81)
QQ/LM	9	3552 (2010 – 5494)	3779 (1606 – 6607)	47 (24 – 63)^a,^b	46 (18 – 87)^a,^b
QQ/MM	5	2411 (1941 – 2842)^a,^b,^c	2982 (2380 – 3992)	38 (31 – 42)^a,^b,^d	38 (32 – 46)^a,^b,^e
QR/LL	11	4593 (1966 – 6348)	4024 (1858 – 5277)	100 (61 – 149)^c	88 (59 – 124)^c
QR/LM	15	3455 (2262 – 5053)^a	3478 (2152 – 4924)	94 (56 – 132)^b,^c,^e	85 (61 – 121)^b,^c,^e
QR/MM	3	1860 (1286 – 2345)^a,^b,^c	1727 (1329 – 2474)^a,^b,^c	57 (46 – 77)^b	47 (32 – 69)^a,^b,^e
RR/LL	12	3909 (2269 – 4643)	4170 (2680 – 5301)	136 (59 – 171)^a,^c	132 (101 – 173)^a,^c
RR/LM	1	1592	1507	78	42
RR/MM	0	-	-	-	-

Data expressed as the mean (range). P-value compares CPOase or POase activity among the different genotypes for the same time period using ANOVA with Tukey post-hoc test.

P ≤ 0.05 compared to QRLL genotype.

P ≤ 0.05 compared to RRLL genotype.

P ≤ 0.05 compared to QQLL genotype.

P ≤ 0.05 compared to QRLM genotype

P ≤ 0.05 compared to QQLM genotype.