Table 2.

Normal hematologic, biochemical and coagulation values in healthy GTKO pigs

	Test	Unit	GTKO	N	GTKO.hCD46	N	GTKO.hCD46.hCD55	N	GTKO.hCD46.hTBM	N	Mean	SD	Total N
Age/Weight			154 days (range 10-647) / 79kg (range 3-247)		72 days (range 18–390) / 8kg (range 3-29)		45 days (range 40-54) / 9kg (range 8-10)		38 days (range 34-41) / 7.5kg (6.4-8.7)		132 days (range 10-647) / 69kg (range 3-247)
Hematology	WBC	/mm3	15.9	71	14.8	17	13.3	4	10.7	2	15.5	1.0	94
	RBC	×106/mm3	6.5	71	5.9	17	4.2	4	5.1	2	6.3	1.4	94
	Hemoglobin	g/dL	12.8	71	11.0	17	6.7	4	9.1	2	12.2	2.5	94
	Hematocrit	%	40.3	71	33.3	17	21.9	4	26.4	2	37.9	8.0	94
	Platelets	×103/mm3	432	71	406	17	444	4	310	2	425	210	94
	MCV	fL	63	71	56	17	53	4	52	2	61.3	9.0	94
	MCH	pg	20	71	19	17	18	4	18	2	19.7	2.3	94
	MCHC	g/dL	32	71	33	17	34	4	34	2	32.3	1.9	94
	RDW	%	18.2	2	21.4	10	22.9	4	21.2	2	21.4	3.7	18
	MPV	fL	9.7	2	9.1	7	9.1	4	9.1	2	9.1	0.8	15
	Neutrophil	%	40.0	71	48.4	17	43.5	4	46.0	2	41.8	13.8	94
	Lymphocyte	%	51.7	71	40.9	17	38.5	4	46.0	2	49.1	15.5	94
	Monocyte	%	5.1	71	4.6	17	4.3	4	2.5	2	4.9	3.1	94
	Eosinophil	%	2.6	71	1.5	17	0.8	4	1.0	2	2.3	2.5	94
	Basophil	%	0.1	71	0.0	17	0.5	4	0.0	2	0.1	0.3	94
Renal Function and Electrolytes	Sodium	mmol/L	146	61	140	18	136	4	140	2	144	7	85
	Potassium	mmol/L	5.6	61	5.1	18	3.3	4	3.8	2	5.3	1.1	85
	Chloride	mmol/L	104	61	101	18	99	4	106	2	103.0	8.0	85
	Calcium	mg/dL	11.0	61	10.4	18	10.0	4	9.7	2	10.8	0.8	85
	Phosphorus	mg/dL	8.9	61	8.5	16	9.2	4	8.5	2	8.8	1.8	83
	CO2	mmol/L	28	61	28	11	30	4	26	2	28	5	78
	Urea	mg/dL	14.6	61	8.8	17	5.8	4	5.5	2	12.8	9.9	84
	Creatinine	mg/dL	1.2	61	0.9	17	0.5	4	0.7	2	1.1	0.5	84
Liver Function	AST	IU/L	38	71	36	18	30	4	36	2	37	29	95
	ALT	IU/L	55	2	40	18	47	4	40	2	42	15	26
	ALP	IU/L	145	2	249	18	409	4	324	2	272	146	26
	LDH	IU/L	559	2	471	9	433	4	468	2	472	109	17
	GGT	IU/L	78	61	65	16	58	4	47	2	74	16	83
	Tot Bilirubin	mg/dL	0.2	61	0.1	9	0.2	4	0.2	2	0.2	0.2	76
	Dir Bilirubin	mg/dL	0.1	61	0.1	9	0.1	4	0.1	2	0.1	0.1	76
	Indir Bilirubin	mg/dL	0.1	61	0.1	9	0.1	4	0.1	2	0.1	0.1	76
	Tot Protein	g/dL	6.2	61	5.5	18	3.9	4	3.8	2	5.9	1.4	85
	Albumin	g/dL	3.8	61	2.8	18	1.3	4	1.3	2	3.4	1.1	85
	Cholesterol	mg/dL	98	2	85	16	62	3	59	2	81	22	23
	Triglyceride	mg/dL	14	2	39	16	14	3	11	2	31	22	23
	Glucose	mg/dL	90	71	93	18	75	4	66	2	89	27	95
Coaulation Profile	PT	sec	14.4	2	13.6	9	13.9	4	13.2	2	13.6	0.5	17
	PTT	sec	32.5	2	34.8	9	35.8	4	29.3	2	34.1	14.0	17
	INR		1.1	2	1.1	9	1.1	4	1.1	2	1.1	0.1	17
	D-Dimer	μg/mL	0.22	2	0.22	9	0.22	4	0.14	2	0.20	0.05	17
	FDP	μg/mL	5to20	2	<5	9	5to20	4			5to20		15
	Fibrinogen	mg/dL	265	71	197	9	156	4	143	2	250	121	86
Others	Amylase	IU/L	459	2	1292	16	2941	4	2780	2	1622	1130	24
	Lipase	IU/L			14	14	10	4	11	2	13.1	13.2	20
	Iron	μg/dL			110	9	79	3	121	2	104.0	48.0	14
	Total CPK	IU/L	1209	59	1228	8	510	4	652	2	1166	2305	73
	CPK-MB isoenzyme	ng/mL			1.2	1	5.1	4	4.8	1	4.4	4.0	6
	CPK-MB relative index				0.1	1	0.9	4	0.6	1	0.7	0.5	6
	Troponin I	ng/mL			0.10	1	0.10	4	0.10	1	0.11	0.02	6