Table 2.
The expression of PER1 protein and its relationship with clinicopathological features of patients with OSCC
| Parameters | cases | PER1 expression | χ2 | P | |
|---|---|---|---|---|---|
|
|
|||||
| Negative | Positive | ||||
| Tissue type | |||||
| Tumor | 41 | 7 | 34 | 7.653 | 0.012 |
| Peritumor | 41 | 0 | 41 | ||
| Age | |||||
| ≥60 | 10 | 2 | 8 | 0.131 | 0.937 |
| 45–60 | 20 | 3 | 17 | ||
| <45 | 11 | 2 | 9 | ||
| Gender | |||||
| Female | 17 | 3 | 14 | 0.007 | 1.000 |
| Male | 24 | 4 | 20 | ||
| Tumor differentiation | |||||
| Well | 13 | 3 | 10 | 0.510 | 0.775 |
| Moderate | 20 | 3 | 17 | ||
| Poor | 8 | 1 | 7 | ||
| T staging | |||||
| T1 + T2 | 18 | 0 | 18 | 6.606 | 0.012 |
| T3 + T4 | 23 | 7 | 16 | ||
| Lymph node metastasis | |||||
| No | 27 | 1 | 26 | 9.982 | 0.004 |
| Yes | 14 | 6 | 8 | ||
| Clinical stage | |||||
| I + II | 22 | 1 | 21 | 5.262 | 0.036 |
| III + IV | 19 | 6 | 13 | ||
Abbreviation: OSCC, oral squamous cell carcinoma.