Table 1.
Summary Statistics by Outcome Analyzed
| |
Outcome |
|
|---|---|---|
| Variable | Pancreatitis | Pancreatic cancer |
| Patients (n) | 268,561 | 209,306 |
| Patient-years (n) | 530,574 | 419,613 |
| Acute pancreatitis hospitalization (%) | 0.247 (4.967) | — |
| Incident pancreatic cancer diagnosis (%) | — | 0.070 (2.651) |
| At least 1 exenatide prescription filled (%) | 2.6 (15.9) | — |
| Cumulative use of 365+ days as of prior year (%) | — | 0.88 (9.35) |
| Patient cost of 30-day exenatide supply | $37.94 ($28.61) | — |
| Patient cost of 30-day supply, prior year | — | $36.56 ($26.99) |
| Age (years) | 63.1 (13.8) | 64.4 (13.5) |
| Male (%) | 54.2 (49.8) | 54.9 (49.8) |
| Years since diabetes diagnosis | 3.1 (3.0) | 4.0 (2.9) |
| History of gallstones (%) | 6.6 (24.5) | — |
| History of alcohol abuse (%) | 5.1 (21.6) | — |
| Co-morbidity history (%) | ||
| Essential hypertension | 61.9 (48.6) | 65.5 (47.6) |
| Congestive heart failure | 8.7 (28.2) | 9.9 (29.9) |
| Asthma | 5.5 (22.9) | 5.8 (23.4) |
| Hypercholesteremia | 50.9 (50.0) | 54.0 (49.8) |
| Ulcer | 1.2 (10.8) | 1.4 (11.6) |
| Depression | 7.9 (26.9) | 8.2 (27.5) |
| Chronic obstructive pulmonary disease | 3.7 (18.8) | 4.1 (19.7) |
| Allergic rhinitis | 6.7 (25.0) | 7.0 (25.5) |
| Arthritis | 16.4 (37.0) | 17.9 (38.3) |
| Cardiac disease | 25.1 (43.4) | 27.7 (44.7) |
| Vascular disease | 4.9 (21.6) | 5.6 (22.9) |
| Gastric acid disorder | 11.9 (32.4) | 12.7 (33.3) |
| Gout | 2.6 (15.9) | 2.8 (16.6) |
| Hyperlipidemia | 50.9 (50.0) | 54.1 (49.8) |
| Thyroid disorder | 10.6 (30.7) | 11.1 (31.4) |
| Rheumatoid arthritis | 1.7 (12.9) | 1.8 (13.2) |
| Human immunodeficiency virus | 0.1 (3.9) | 0.1 (3.8) |
| Anemia | 11.9 (32.4) | 13.3 (34.0) |
| Stroke | 7.1 (25.7) | 8.0 (27.1) |
In pancreatitis analysis, outcome is hospitalization for acute pancreatitis; in pancreatic cancer analysis, outcome is incident pancreatic cancer diagnosis. SDs are in parentheses. Costs are in 2010 dollars.