Table 4.
|
Analysis by dependent variable |
|||
---|---|---|---|---|
|
Pancreatitis |
Pancreatic cancer |
||
Exenatide usea | Health outcome | Exenatide usea | Health outcome | |
Odds ratio (95% confidence interval) | ||||
Constant | 0.031 (0.030–0.032)‡ | 0.003 (0.002–0.003)‡ | 0.011 (0.010–0.011)‡ | 0.0007 (0.0006–0.0008)‡ |
High out-of-pocket costb | 0.711 (0.679–0.745)‡ | 0.934 (0.835–1.046) | 0.672 (0.614–0.735)‡ | 1.072 (0.853–1.347) |
Predictive margins | ||||
Low cost | 3.0% | 0.256% | 1.1% | 0.068% |
High cost | 2.2% | 0.239% | 0.7% | 0.073% |
Other statistics | ||||
Patient-years (n) | 530,574 | 530,574 | 419,613 | 419,613 |
In pancreatitis analysis, outcome is hospitalization for acute pancreatitis; in pancreatic cancer analysis, outcome is incident pancreatic cancer diagnosis.
Exenatide use is defined for pancreatitis as at least one exenatide prescription filled and for pancreatic cancer as cumulative use of 365+ days as of the prior year.
High out-of-pocket cost is defined as patient cost of 30-day exenatide supply above the median level in the pancreatitis analysis and as cost in the prior year above the median in the pancreatic cancer analysis.
Statistical significance is defined at the ‡1% level.