Table 1.
The primaquine therapies.
| Therapy | Intent | Dose* | Duration | G6PD Safety | Notes |
|---|---|---|---|---|---|
| Gametocytocidal | Anti-transmission | 45 mg | Single | Otherwise healthy A-men | No proven clinical or public health benefit |
| Hypnozoitocidal | Anti-relapse | 15 mg daily | 5 days | Unknown | No known efficacy, no longer used |
| 15 mg daily | 14 days | None, except cessation | Korean, Indian & American strains |
||
| 30 mg daily 45 mg weekly |
14 days 8 weeks |
None, except cessation Otherwise healthy A-men |
Tropical Asian strains Efficacy not widely proven |
||
| Causal prophylactic | Prevention in travelers |
30 mg daily | Up to 50 weeks | None, except cessation | Unlicensed indication |
*
All doses as subscribed for adults weighing 40 to 70 kg, mean of 60 kg.