Table 4.
Relationship between mannose-binding lectin concentrations and hospitalization for acute exacerbations of chronic obstructive pulmonary disease
| Total subjects | Subjects n (%) | MBL concentration (ng/mL) | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| 1037 |
≤50 5 |
>50 1032 |
≤100 20 |
>100 1017 |
≤500 251 |
>500 786 |
>50 ≤1000 542 |
>1000 490 |
|
| Subjects requiring hospitalization, n (% ) | 220 (21%) | 1 (20%) | 219 (21%) | 4 (20%) | 216 (21%) | 47 (19%) | 173 (22%) | 106 (20%) | 113 (23%) |
| Subjects receiving azithromycin and requiring hospitalization, n (% of subjects receiving azithromycin) | 520 | 1 | 519 | 8 | 512 | 106 | 414 | 258 | 261 |
| 103 (20%) | 0 (0%) | 103 (20%) | 1 (13%) | 102 (20%) | 19 (18%) | 84 (20%) | 47 (18%) | 56 (21%) | |
| Subjects receiving placebo and requiring hospitalization, n (% of subjects receiving placebo) | 517 | 4 | 513 | 12 | 505 | 145 | 372 | 284 | 229 |
| 117 (23%) | 1 (25%) | 116 (23%) | 3 (25%) | 114 (23%) | 28 (19%) | 89 (24%) | 59 (21%) | 57 (25%) | |
Abbreviation: MBL, mannose-binding lectin.