Figure 1.

The TAP tag–based Hsp70/Hsp110 interaction network. The main figure shows the hits obtained from the TAP tag pull-down of the nine Hsp70s/Hsp110s. The hits are grouped according to Gene Ontology categories (also shown in the bottom graph; The Gene Ontology Consortium, 2000) and are organized into complexes as defined by Pu et al. (2009; bottom right inset). The overlap in the hits between N- and C-tagged chaperones is shown in the bottom left. Data are from experiments completed once. Complexes identified are shown in the top right inset. FACT, facilitates chromatin transcription; NER, nucleotide excision repair; snoRNP, small nucleolar ribonucleoprotein; SCF, Skp, Cullin, F-box–containing complex.