Table 4.
Differences in expression between ICM and TE for genes involved in segregation of ICM and TE in micea
| Gene symbol | Role in mouse | Mean counts, ICM | Mean count, TE | Fold change, TE/ICM | Adjusted P value |
|---|---|---|---|---|---|
|
CDX2 |
TE commitment |
5.7 |
2.8 |
0.49 |
0.780 |
|
ELF5 |
TE differentiation |
5.3 |
28.9 |
5.41 |
0.022 |
|
GATA3 |
TE commitment |
363.6 |
976.7 |
2.69 |
0.018 |
|
EOMES |
TE differentiation |
1.4 |
0.2 |
0.16 |
0.934 |
|
NANOG |
ICM commitment |
3014.8 |
620.9 |
0.21 |
0.000 |
|
POU5F1 |
ICM commitment |
2394.1 |
1873.5 |
0.78 |
0.605 |
|
SALL4 |
ICM commitment |
5.3 |
3.8 |
0.71 |
0.893 |
|
SOX2 |
ICM commitment |
816.2 |
360.7 |
0.44 |
0.005 |
|
TEAD4 |
TE commitment |
7.1 |
12.0 |
1.69 |
0.894 |
| YAP1 | TE commitment | 47.9 | 43.0 | 0.90 | 1.000 |
a Source: Chen et al. [7].