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. 2012 Dec 4;7(12):e51177. doi: 10.1371/journal.pone.0051177

Figure 2. Pulsed ultrasonic neurostimulation elicits ultrasound-evoked potentials.

Figure 2

(A) Grand average of ultrasound-evoked potentials (USEPs) recorded from five subjects using a 64 channel EEG in response to right (black traces) and left (cyan traces) fingertip stimulation using a PUNS-M waveform are shown in a top-view of the whole-head. The channels indicated by the red square are shown at a higher gain in B. The vertical dashed lines represent the onset of stimulation and the EEG traces illustrate a time period from 100 msec pre-stimulus to 1000 msec post-stimulus. (B) Grand average USEPs from electrode sites C3, CZ, and C4 shown in A, but at a higher amplitude and temporal gain. The vertical dotted lines show time points of interest for which average voltage maps are shown in C and labels (P1, N1, N2, and P2) indicate potentials of interest. (C) Topographic voltage maps from time-points corresponding to vertical dotted lines in B illustrate grand average USEPs obtained in response to PUNS-M stimulation of the left (top) and right (bottom) fingers.