Table 6. Standardized mortality ratios (SMRs) in overall and subpopulation of IgAN patients.
N | Initial age | Final age | Person-year | Observed | Expected | SMR(95% CI) | ||
Overall | 1009 | 36.8±13.7 | 45.0±14.0 | 8134.2 | 44 | 30.7 | 1.43(1.04–1.92) | |
eGFR | ≥60 | 606 | 32.9±12.2 | 41.3±13.2 | 5077.4 | 15 | 13.8 | 1.08(0.61–1.79) |
<60 | 374 | 43.4±13.6 | 50.9±13.2 | 2825.6 | 28 | 16.5 | 1.70(1.13–2.46) | |
Proteinuria | <1 g/day | 341 | 33.8±13.1 | 41.0±13.3 | 2445.5 | 6 | 6.2 | 0.97(0.36–2.12) |
≥1 g/day | 572 | 39.1±13.7 | 47.7±13.7 | 4941.5 | 36 | 21.7 | 1.66(1.16–2.29) | |
SBP | <140 | 768 | 35.2±13.1 | 42.8±13.4 | 5911.3 | 18 | 18.3 | 0.98(0.58–1.56) |
≥140 | 230 | 42.2±14.1 | 51.4±13.9 | 2125.2 | 23 | 12.3 | 1.88(1.19–2.82) | |
Men | 495 | 36.1±14.7 | 45.0±15.0 | 4403.6 | 29 | 23.8 | 1.22(0.82–1.75) | |
eGFR | ≥60 | 309 | 31.6±12.9 | 40.7±13.6 | 2827.9 | 10 | 10.2 | 0.98(0.47–1.81) |
<60 | 173 | 44.6±14.0 | 53.1±13.5 | 1482.8 | 18 | 13.4 | 1.34(0.80–2.13) | |
Proteinuria | <1 g/day | 143 | 31.5±13.7 | 40.1±14.0 | 1225.5 | 3 | 1.9 | 1.57(0.32–4.58) |
≥1 g/day | 307 | 38.7±14.4 | 47.8±14.3 | 2791.7 | 12 | 4.6 | 2.60(1.35–4.55) | |
SBP | <140 | 356 | 34.4±14.3 | 43.0±14.5 | 3092.0 | 12 | 14.1 | 0.85(0.44–1.49) |
≥140 | 135 | 40.6±14.9 | 50.2±14.6 | 1299.1 | 15 | 9.7 | 1.55(0.87–2.56) | |
Women | 514 | 37.5±12.6 | 45.0±13.0 | 3730.6 | 15 | 6.9 | 2.17(1.21–3.57) | |
eGFR | ≥60 | 297 | 34.4±11.3 | 41.9±12.7 | 2249.5 | 5 | 3.7 | 1.36(0.44–3.18) |
<60 | 201 | 42.4±13.2 | 49.0±12.8 | 1342.8 | 10 | 3.1 | 3.24(1.55–5.95) | |
Proteinuria | <1 g/day | 198 | 35.5±12.4 | 41.6±2.9 | 1220.0 | 3 | 4.2 | 0.71(0.15–2.07) |
≥1 g/day | 265 | 39.4±12.7 | 47.5±13.0 | 2149.8 | 24 | 17.1 | 1.40(0.90–2.08) | |
SBP | <140 | 412 | 35.9±12.0 | 42.7±12.4 | 2819.3 | 6 | 4.2 | 1.43(0.53–3.12) |
≥140 | 95 | 44.5±12.5 | 53.1±12.7 | 826.1 | 8 | 2.6 | 3.09(1.34–6.10) |
Abbreviations: SMR, standardized mortality ratio; CI, confidence interval; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure.