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. 2012 Dec 4;7(12):e51225. doi: 10.1371/journal.pone.0051225

Table 6. Standardized mortality ratios (SMRs) in overall and subpopulation of IgAN patients.

N Initial age Final age Person-year Observed Expected SMR(95% CI)
Overall 1009 36.8±13.7 45.0±14.0 8134.2 44 30.7 1.43(1.04–1.92)
eGFR ≥60 606 32.9±12.2 41.3±13.2 5077.4 15 13.8 1.08(0.61–1.79)
<60 374 43.4±13.6 50.9±13.2 2825.6 28 16.5 1.70(1.13–2.46)
Proteinuria <1 g/day 341 33.8±13.1 41.0±13.3 2445.5 6 6.2 0.97(0.36–2.12)
≥1 g/day 572 39.1±13.7 47.7±13.7 4941.5 36 21.7 1.66(1.16–2.29)
SBP <140 768 35.2±13.1 42.8±13.4 5911.3 18 18.3 0.98(0.58–1.56)
≥140 230 42.2±14.1 51.4±13.9 2125.2 23 12.3 1.88(1.19–2.82)
Men 495 36.1±14.7 45.0±15.0 4403.6 29 23.8 1.22(0.82–1.75)
eGFR ≥60 309 31.6±12.9 40.7±13.6 2827.9 10 10.2 0.98(0.47–1.81)
<60 173 44.6±14.0 53.1±13.5 1482.8 18 13.4 1.34(0.80–2.13)
Proteinuria <1 g/day 143 31.5±13.7 40.1±14.0 1225.5 3 1.9 1.57(0.32–4.58)
≥1 g/day 307 38.7±14.4 47.8±14.3 2791.7 12 4.6 2.60(1.35–4.55)
SBP <140 356 34.4±14.3 43.0±14.5 3092.0 12 14.1 0.85(0.44–1.49)
≥140 135 40.6±14.9 50.2±14.6 1299.1 15 9.7 1.55(0.87–2.56)
Women 514 37.5±12.6 45.0±13.0 3730.6 15 6.9 2.17(1.21–3.57)
eGFR ≥60 297 34.4±11.3 41.9±12.7 2249.5 5 3.7 1.36(0.44–3.18)
<60 201 42.4±13.2 49.0±12.8 1342.8 10 3.1 3.24(1.55–5.95)
Proteinuria <1 g/day 198 35.5±12.4 41.6±2.9 1220.0 3 4.2 0.71(0.15–2.07)
≥1 g/day 265 39.4±12.7 47.5±13.0 2149.8 24 17.1 1.40(0.90–2.08)
SBP <140 412 35.9±12.0 42.7±12.4 2819.3 6 4.2 1.43(0.53–3.12)
≥140 95 44.5±12.5 53.1±12.7 826.1 8 2.6 3.09(1.34–6.10)

Abbreviations: SMR, standardized mortality ratio; CI, confidence interval; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure.