Table 2.
Limited virucidal activity of glutardialdehyde and formaldehyde against duck hepatitis B virus (DHBV) depending on concentration and contact time in comparison to vaccinia virus (VACV)/modified vaccinia Ankara strain (MVA)
| Biocide | Concentration (%) | Contact time (min) |
Reduction factors |
|
|---|---|---|---|---|
| DHBV | VACV/MVA | |||
| Glutardialdehyde |
0.05 |
0.5 |
2.79 ± 0.78 |
1.62 ± 0.25/1.14 ± 0.29 |
| |
2 |
≥4.05 |
≥4.35/≥3.82 |
|
| |
5 |
≥4.05 |
≥4.35/≥3.82 |
|
| 0.1 |
0.5 |
≥4.05 |
2.91±0.22 / 2.21±0.25 |
|
| |
2 |
≥4.05 |
≥4.35 / ≥3.82 |
|
| |
5 |
≥4.05 |
≥4.35 / ≥3.82 |
|
| Formaldehyde |
0.7 |
5 |
2.00 ± 0.40 |
1.15 ± 0.28/≥2.09 |
| |
30 |
≥3.06 |
>2.62/>2.14 |
|
| 60 | ≥3.08 | >3.16/>2.14 | ||
Results for VACV and MVA are given as means calculated from the results of three different laboratories (Rabenau et al. [10]).
“≥” - Determination of RF is limited by hepatocytotoxic reactions and/or the amount. Calculation of 95% confidence interval is not possible.