Table 2.
Drugs shown not to inhibit cough reflex sensitivity to capsaicin
| 1st author | Ref. # | Year | Drug | Subject population |
|---|---|---|---|---|
| Ryan M |
[38] |
2012 |
gabapentin |
chronic cough |
| Yousaf N |
[39] |
2010 |
erythromycin |
chronic cough |
| Dicpinigaitis P |
[10] |
2009 |
benzonatate |
viral URI |
| Dicpinigaitis P |
[12] |
2008 |
tiotropium |
healthy volunteers |
| Davenport P |
[40] |
2007 |
codeine |
healthy volunteers |
| Dicpinigaitis P |
[41] |
2003 |
fexofenadine |
healthy volunteers |
| Dicpinigaitis P |
[17] |
2003 |
guaifenesin |
healthy volunteers |
| Ishiura Y |
[18] |
2003 |
ambroxol |
asthma |
| Ishiura Y |
[19] |
2003 |
pranlukast |
chronic bronchitis |
| Dicpinigaitis P |
[42] |
2001 |
celecoxib |
asthma |
| Fujimura M |
[43] |
2000 |
mexiletine |
healthy volunteers |
| Dicpinigaitis P |
[44] |
1999 |
zafirlukast |
asthma without cough |
| Capon D |
[45] |
1996 |
dextromethorphan |
healthy volunteers |
| Hansson L |
[46] |
1994 |
nicotine |
healthy nonsmokers |
| Hutchings H |
[47] |
1994 |
codeine |
healthy volunteers |
| O’Connell F |
[48] |
1994 |
clonidine |
healthy volunteers |
| Fujimura M |
[49] |
1993 |
procaterol |
asthma, chronic bronchitis |
| Choudry N |
[50] |
1993 |
MAO inhibitors |
healthy volunteers |
| Stone R |
[51] |
1993 |
5-HT (serotonin) |
healthy volunteers |
| Fujimura M |
[52] |
1992 |
procaterol |
healthy volunteers |
| Ventresca P |
[53] |
1992 |
furosemide |
healthy volunteers |
| Karlsson J |
[54] |
1992 |
furosemide, HCTZ |
healthy volunteers |
| Studham J |
[55] |
1992 |
terfenadine |
healthy volunteers |
| Choudry N |
[56] |
1991 |
inhaled mu opioid agonist |
healthy volunteers |
| Smith C |
[57] |
1991 |
salbutamol, ipratropium |
healthy volunteers |
| Choudry N |
[58] |
1991 |
granisteron (5-HT3) |
healthy volunteers |
| McEwan J |
[35] |
1990 |
sulindac |
idiopathic cough |
| Hansson L |
[59] |
1988 |
nedocromil |
healthy volunteers |
| Fuller R |
[37] |
1988 |
inhaled opiates |
healthy volunteers |
| Collier J | [4] | 1984 | sodium cromoglycate | healthy volunteers |
Abbreviations: URI-acute upper respiratory tract infection; MAO-monoamine oxidase; HCTZ-hydrochlorothiazide.