Table 1.
Base case input parameters
|
Base Case Modifiable Inputs | ||||
|---|---|---|---|---|
| LFA | RIS-LAI | RIS-SOT | Source | |
| Adherence |
1.0* |
0.85* |
0.65** |
**
[21] |
| Annual Discontinuation (Persistence) |
0.30 |
0.50 |
0.64 |
[20,23] |
|
Annual Relapse Rates | ||||
| When Adherent |
10.10% |
|
|
[15] |
| When Non-adherent |
78.70% |
|
|
|
| Proportion of Relapses Inpatient |
0.53 |
|
|
|
|
Utilities | ||||
| |
While Stable |
In Inpatient Relapse |
In Outpatient Relapse |
|
| Adherent |
0.88 |
0.53 |
0.74 |
[24] |
| Non-adherent |
0.75 |
0.42 |
0.63 |
|
|
Execution | ||||
| Model Timeframe |
5 years |
N/A | ||
| Cycle Length |
1.0 months |
|||
| Discount rate (costs) | 3% | |||