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. Author manuscript; available in PMC: 2013 Nov 16.

Published in final edited form as: ACS Chem Biol. 2012 Oct 5;7(11):1918–1928. doi: 10.1021/cb300340j

Inhibition of FtsZ GTPase activity by 24 μM and 64 μM totarol at increasing FtsZ concentrations. A) BsFtsZ, B) EcFtsZ. The slight downward trend for DMSO only can be explained by increased bundling of FtsZ protofilaments at the higher concentrations, which can lead to slower nucleotide exchange⁷³.

Inhibition of FtsZ GTPase activity by 24 μM and 64 μM totarol at increasing FtsZ concentrations. A) BsFtsZ, B) EcFtsZ. The slight downward trend for DMSO only can be explained by increased bundling of FtsZ protofilaments at the higher concentrations, which can lead to slower nucleotide exchange⁷³.