Figure 2. Fabp4-cre is widely expressed prenatally and postnatally.

(a–j) Cre-mediated β-gal reporter expression showing cre recombination outside white and brown adipose tissue in Fabp4-cre/ROSA26 mice. (a) Histological sections at E10.5 showing β-gal reporter expression in the inferior hindbrain (arrow head), trunk mesenchyme (arrowhead), somites (arrowhead), spinal column and developing dorsal root ganglion (arrowhead). (b) Histological sections at E15.5 showing wide ranging cre activity throughout the central nervous system (arrowhead), inner ear (arrowhead), thyroid gland (arrowhead), vertebra (arrowhead), ribs (arrowhead) and interstitial cells of the testis (arrowhead). (c–f) Selected tissues of postnatal day 7 (P7) mice displaying β-gal expression throughout the spinal column (c), myocardium (d), epithelial and smooth muscle cells of the gut (e), interstitial cell of the ovary, uterine glandular epithelium, myometrium and endometrial cells of the uterus (f) (arrowheads). (g–j) Selected tissues of Adult (P56) mice exhibiting cre activity throughout the brain (g), skeletal muscle (h), islets of Langerhan’s, pancreatic ducts (i) (arrowhead), interstitial cells of the testis and vascular endothelium (j) (arrowhead).