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Inconsistent cre activity in E10.5 littermates in Tek-cre and Vav1-cre strains. E10.5 embryos collected from timed matings between R26R-lacZ female mice and male mice harbouring the cre allele indicated. (a,b) Tek-cre/R26R-lacZ littermates exhibiting restricted (a) or homogenous and (b) β-gal expression. (c,d) Vav1-cre/R26R-lacZ littermates displaying β-gal restricted to hepatic primordium (c) or mosaic expression throughout embryo (d).
