Table 1.

Simulation parameters taken from external analysis of experimental results

Parameter		Value [μM−1 s−1]	Ref.
Association rate constants
Barbed G-ATP	bk+T	11.6	Pollard (32)
Barbed G-ADPPi	bk+P	3.4	Fujiwara et al. (1)
Barbed G-ADP	bk+D	2.9	Fujiwara et al. (1)
Pointed G-ATP	pk+T	1.3	Pollard (32)
Pointed G-ADPPi	pk+P	0.11	Fujiwara et al. (1)
Pointed G-ADP	pk+D	0.14	Fujiwara et al. (1)
Parameter		Value [s−1]	Ref.
Dissociation rates
Barbed F-ATP	bk−T	1.4	Pollard (32)
Barbed F-ADPPi	bk−P	0.2	Fujiwara et al. (1)
Barbed F-ADP	bk−D	5.4	Fujiwara et al. (1)
Pointed F-ATP	pk−T	0.8	Pollard (32)
Pointed F-ADPPi	Pk−P	0.02	Fujiwara et al. (1)
Pointed F-ADP	Pk−D	0.25	Fujiwara et al. (1)
Barbed Pi	brd	2	Fujiwara et al. (1)
Pointed Pi	prd	2	Fujiwara et al. (1)
Other parameters
Cleavage rate	rc	0.3	Blanchoin and Pollard (33)

Note that the barbed-end Pi dissociation rate was varied for some simulations.