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. Author manuscript; available in PMC: 2012 Dec 5.
Published in final edited form as: Biochemistry. 2006 Jan 24;45(3):871–879. doi: 10.1021/bi0512703

Figure 2.

Figure 2

Graphical representation of the ensemble average ΔΔG (kcal/mol) values for substitution of individual bases with a library of other natural bases. The inset graph shows the relative binding constants at each position.