Association between genotype, the prevalence of red complex periodontopathogens, and GCF IL-1β levels in patients with GO. The box represents the first and the third quartiles (rectangular boxes); the line within the box is the median and the little circles represent atypical values that were plotted separately. * denotes p< 0.05 by Mann-Whitney U test. GCF, gingival crevicular fluid; IL-1β, interleukin-1β. Pg, Porphyromonas gingivalis; Td, Treponema denticola; Tf, Tannerella forsythia;