Figure 1.
Effect of PPIX and 5-ALA on XIAP protein levels in normal and malignant prostate epithelial cells. (A) Effect of PPIX and 5-ALA treatment on the expression of XIAP in PC-3, DU-145 (malignant) and PZ-HPV-7 (normal) prostate epithelial cells. Cells were cultured in medium alone or in the presence of either PPIX (50µM) or 5-ALA (200µM) for 24 hours. Expression of XIAP and GAPDH was detected by immunoblotting with specific antibodies. Expression of GAPDH was used to document equal protein loading. (B) Structures of 5-ALA and the derivatives.
