Table 1.
PPIX accumulation in malignant and normal prostate epithelial cells followed by administration of 5-ALA and derivatives at 200µM for 1 hour. Numerical values represent mean percentage PPIX positive cells ± SD (range).
| CELL LINES |
5-ALA AND DERIVATIVES | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Med | 5- ALA |
ALA- ME |
ALA- EE |
ALA- PE |
ALA- BE |
ALA- HE |
ALA- TE |
Ac- ALA-Am |
Pen- ALA-Am |
|
| PC-3 | 1.84±0.14 | 43.35±5.89 | 5.30±0.16 | 4.91±0.46 | 27.53±1.36 | 63.94±1.91 | 98.66±0.10 | 2.25±0.28 | 2.26±0.30 | 2.10±0.26 |
| DU-145 | 2.85±0.11 | 26.79±1.09 | 7.92±8.88 | 3.23±0.51 | 22.02±0.74 | 57.09±4.11 | 90.89±1.48 | 2.63±0.20 | 2.59±0.18 | 2.55±0.18 |
| LNCaP | 1.04±0.33 | 9.01±0.54 | 2.29±0.54 | 49.49±1.43 | 81.75±0.79 | 77.87±1.46 | 79.74±1.69 | 2.14±0.98 | 2.54±0.32 | 2.57±0.71 |
| PZ-HPV-7 | 2.00±0.15 | 7.36±0.49 | 1.70±0.14 | 9.32±0.32 | 23.17±3.89 | 24.99±0.76 | 26.93±3.86 | 1.34±0.05 | 1.69±0.08 | 1.55±0.16 |