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. 2012 Dec 5;6:82. doi: 10.3389/fncir.2012.00082

Table 2.

Characteristics of rodent neocortical GABAergic neurons expressing neuronal nitric oxide synthase.

Markers % cells within nNOS-type II Morphology Axonal targeting Firing pattern* Transcription factors or lineage markers Place of genesis
Highly Long projection1,2 Blood vessels1,2 Late spiking3,8 Nkx2.1/Lhx63,4,5 MGE3,4,5
nNOS+SOM+/NPY+3,4,5,6,7,8 Neurons1,2 Adapting3,8
(nNOS-type I)
Lightly nNOS+ 55 Neurogliaform3,6 Blood vessels ? Adapting3,8 Nkx2.1/Lhx63,4 MGE3,4
NPY+3,5,6,8,9 Dentritic shaft 5-HT3A3,4,6 CGE/AEP3,4
(nNOS-type II)
Lightly nNOS+ PV+ or SOM+3,5,6,8,10 (nNOS-type II) 35 Multipolar3 Blood vessels ? Proximal dendrites Soma Axonal initial segment Fast spiking3 Nkx2.1/Lhx63,4 MGE3,4
Lightly nNOS 10 Bipolar3,6 Blood vessels ? Adapting3 5-HT3A3,4,6 AEP/PO? 3
VIP+/CR+3,5,6,8 Double-bouquet3,6 Soma CGE3,4
(nNOS-type II) SVZ/Ctx?
*

Firing pattern elicited from intracellular injections of depolarizing currents: AEP, entopeduncular area; CGE, caudal ganglionic eminence; Ctx, cortex; LGE, lateral ganglionic eminence; MGE, medial ganglionic eminence; POA, preoptic area; SVZ, subventricular zone.

1

Tomioka et al., 2005,

2

Higo et al., 2009,

3

Perrenoud et al., 2012a,

4

Magno et al., 2012,

5

Jaglin et al., 2012,

6

Perrenoud et al., 2012b,

7

Kubota et al., 2011,

8

Karagiannis et al., 2009,

9

Oláh et al., 2009,

10

Vruwink et al., 2001.