Results of latent class analysis of offspring substance use and psychiatric disorder (N=831).
AUD=alcohol abuse or dependence
MJABDEP=marijuana abuse or dependence
ND=nicotine dependence
CD=conduct disorder
ANX=anxiety disorder (social phobia, panic disorder, or generalized anxiety disorder)
MDD=major depressive disorder
Based on patterns of endorsement probabilities, Class 1 (grey line) was defined as ‘Unaffected’, Class 2 (dashed line) was defined as ‘AUD’, Class 3 (dotted line) was defined as ‘AUD-MDD-ANX’ and Class 4 (solid line) was defined as substance use disorder ‘(SUD)-CD’, see text for details.
Numbers in parenthesis are the proportion of offspring in each class